The Promise of Hydroxychloroquine (Plaquenil) For Covid-19

Hydroxychloroquine

There is a plethora of information on the web about Hydroxychloroquine (HCQ), also called Plaquenil, when it comes to the desperate search for something effective against Covid19. However, there is scant data about how HCQ works on the SARS Coronavirus-2 (SARS-CoV2) from peer-reviewed journals.

This web-link (below) references a very recent and relatively well conducted Chinese study, in which HCQ appears to shorten the course of the disease. However, it is difficult to tell if it also helps reduce severity or prevent progression to acute respiratory distress syndrome (ARDS). There were only 62 participants, which is not a sufficiently powerful study, but it is a start.

Some of the skeptics of HCQ state that the side effects are particularly problematic for those that are critically ill. And justifiably, like most drugs, there are some significant potential adverse effects, including heart arrhythmias. Despite these concerns, the limited data showed that there were only two mild reactions (a rash and a headache) among all of the participants in the Chinese study.

While acknowledging a need for large-scale clinical trials and other research to clarify the specific treatment mechanism and optimize the treatment plan, the authors of the study concluded that “considering that there is no better option at present, it is a promising practice to apply HCQ to COVID-19 under reasonable management.”

The US President has openly recommended HCQ use, which would be extremely premature under normal circumstances.  However, given that we are in crisis mode, it very well may be a reasonable approach to employ, at least for those with more severe cases of Covid-19..

Below is a link to the Chinese study referenced above.  Questions or comments are encouraged so that we can learn together as a community.

https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v2.full.pdf

Take a look at our Covid-Page for a volume of fact-checked authoratative information about Covid-19.

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Justin Groode MD | Patient Advocate Alliance LLC

This Post Has 4 Comments

  1. I’m really inspired together with your writing skills and also with the structure for your blog. Is that this a paid theme or did you modify it your self? Anyway keep up the nice high quality writing, it is rare to peer a great blog like this one nowadays.

    1. Justin Groode

      Thank you so much for your feedback, it is very appreciated! I am one of the founders of PAA and am responsible for writing most of the blog posts.
      Justin Groode

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